Carcinoma nasofaríngeo. Rev Med Cos Cen ; 72 (). Language: Español References: Page: PDF: Kb. [Full text – PDF]. ABSTRACT. Since its discovery 50 years ago, Epstein-Barr virus (EBV) has been linked to the development of cancers originating from both lymphoid and epithelial cells. Request PDF on ResearchGate | Carcinoma nasofaríngeo familiar en zona no endémica. Presentación de 3 familias | Nasopharyngeal carcinoma is the.

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EBV can colonize the memory B-cell pool in vivo and efficiently transform resting B cells into permanent, latently infected lymphoblastoid cell lines LCLs in vitro —characteristics mirrored in the various malignancies of B-cell origin that are closely associated with EBV infection [2][3][5].

The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation. Comprehensive management of head and neck tumors. Lesions of the head and neck in patients with AIDS: Report of a case-control study in Hong Kong”. Novel therapeutic approaches using virus reactivation [96]gene therapy [97]or therapeutic vaccination [98] augur well for our ability to effectively target EBV-associated carcinomas, and mass screening programs to identify patients with early-stage NPC are already underway in Hong Kong [99].

La Risonanza Magnetica RMN permette una miglior visuale dei tessuti molli, avendo raggiunto nella sua ultima versione DWI un buon livello di risoluzione [93]. Although rare, NPC accounts for about one third of childhood nasopharyngeal neoplasms. Epstein-Barr virus-associated antibody patterns in carcinoma of the post-nasal space.

Type 1 I is keratinizing squamous cell carcinoma. Keratinizing squamous cell carcinoma Nonkeratinizing squamous cell carcinoma Differentiated subtype Undifferentiated subtype Basaloid squamous cell carcinoma Undifferentiated is the most common subtype.

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Nasopharynx cancer

Incidence is higher in the Chinese and Tunisian populations. URL consultato il 14 febbraio J Laryngol Otol ; However, it is the undifferentiated form of nasopharyngeal carcinoma NPC that shows the most consistent worldwide association with EBV. CK7CK20 Other negative stains may be useful to rule out darcinoma URL consultato il 16 febbraio Head and neck cancer of respiratory tract Epstein—Barr virus-associated diseases Infectious causes of cancer Pharynx.

EN C00 – C Check this box if you wish to receive a copy of your message. Frequent chromosome 9p losses in histologically normal nasopharyngeal epithelia from Southern Chinese.

Epstein-Barr virus and nasopharyngeal carcinoma

Invasione delle strutture adiacenti spazi masticatori, spazi pterigoidei, base del cranio; inglobamento carotide interna. Page views in Prosthetic rehabilitation following tumor resectionin Schweiz Monatsschr Zahnmedvol.

Services on Demand Journal. Pancoast tumor Solitary pulmonary nodule Central lung Peripheral lung Bronchial leiomyoma. Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the carcinomma of side population stem-like cancer cells in nasopharyngeal carcinoma.

Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways. The study of EBV and its role in carcinomas continues to provide insight into the carcinogenic process that is relevant to a broader understanding of tumor pathogenesis and to the development of targeted cancer therapies.

New author database being installed, click naxofaringeo for details. Non frequenti comunque le metastasi a distanza. Am J Otol ; Differentiation means how different the cancer cells are from normal cells.

Anatomy regional and applied. MRI covering the nasopharynx and cervical regions is preferred imaging modality to assess extent of disease and presence of intracranial extension Radiopaedia: Seminars in Cancer Biology.

Frequentemente i diversi aspetti possono coesistere, rendendo difficile classificare il diverso grado di differenziazione.


Eur J Radiol ;9: Much of our understanding of the biology of EBV relates to its interaction with B lymphocytes. The expression of EBV latent proteins within undifferentiated nasopharyngeal carcinoma can be potentially exploited for immune-based therapies.

Carcinoma della bocca

Such intertypic recombination has been reported in HIV-infected patients and in the Chinese population, and appears to nasoofaringeo via recombination of multiple EBV strains during the intense EBV replication that results from immunosuppression [73].

URL consultato il 12 febbraio Very rarely does Epstein-Barr virus lead to cancer, which suggests a variety of influencing factors. Author information Article jasofaringeo Copyright and License information Disclaimer. Studies on the role of infection in cancer continue to reveal the underlying mechanisms that drive the oncogenic process and to highlight opportunities for therapeutic and prophylactic intervention.

Signs and symptoms related to the primary tumor include trismuspain, otitis medianasal regurgitation due to paresis loss of or impaired movement of the soft palatehearing loss and cranial nerve palsy paralysis. Nasopharyngeal carcinoma risk by histologic type in central China: In particolare il livello di coinvolgimento linfonodale sembra essere un indicatore particolarmente significativo [].

Nasofarinyeo occurs in children and adults. Carcinoma of the nasopharynx.

The prominent lymphoid infiltrate in NPC is believed to contribute to the growth and survival of the tumor cells. URL consultato il 12 marzo Historical Background InTony Epstein and Yvonne Barr identified herpesvirus-type particles by electron microscopy in a subpopulation of Burkitt lymphoma BL -derived tumor cells in vitro.

Sarcoma Lymphoma Immature teratoma Melanoma.