Ephaptic coupling of cortical neurons. Article (PDF Available) in Nature Neuroscience 14(2) · February with Reads. Request PDF on ResearchGate | Ephaptic Coupling of Cortical Neurons: Possible Contribution of Astroglial Magnetic Fields? | The close. Yet the extracellular field activity feeds back onto the electrical potential across the neuronal membrane via ephaptic coupling (Jefferys et al.
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Showing of 3 extracted citations. The relationship between local field potentials LFPs and the electromagnetic fields that give rise to them Neurkns G. Cable theory is one of the most important mathematical equations in neuroscience. Su found the same interactions in four other types of sensilla in the fruit fly, as well as one in the malarial mosquito Anopheles gambiae.
From Wikipedia, the free encyclopedia. More recent research, however, has focused on the more general case of electric fields that affect a variety of coftical. This page was last edited on 11 Novemberat Hence it is a hypothesis that neurobiology and evolution of brain coped with ways of preventing such synchronous behavior on large scale, using it rather in other special cases.
A number of studies neurojs shown how inhibition among neurons in the olfactory system work to fine tune integration of signals in response to odor. Ephaptic Coupling of Cortical Neurons: This action requires you to be registered with Frontiers and logged in.
This effect was not quantitatively explored, however, until experiments by Katz and Schmitt  inwhen the two explored the electric interaction of two adjacent limb nerves of the crab Carcinus maenas. Angel NeurosShira Knafo Neuroscience Simultaneous action potential firing caused interference and resulted in decreased conduction velocitywhile slightly offset stimulation resulted in synchronization of the two impulses.
A similar ephaptic effect has been studied in the Mauthner cells of teleosts. Our results support the notion that ephaptic coupling to endogenous electric fields in the brain may crucially impact neural communication.
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Ephaptic coupling in cortical neurons
From This Paper Topics from this paper. Ephaptic coupling is a form of communication within the nervous system and is distinct from direct communication systems like electrical synapses and chemical synapses. Depending on the location and identity of the neurons, various mechanisms have been found to underlie ephaptic inhibition.
These changes were attributed to the local currents coortical form the action potential. Knowing the role that ephaptic coupling plays in maintaining synchrony in electrical signals, it makes sense to look for ephaptic mechanisms in this type of pathology. The inhibition due to ephaptic coupling would help account for the integration of signals that gives rise to more nuanced perception of smells.
Studies of ephaptic coupling have also focused on its role in the synchronization and timing of action potentials in neurons. It may refer to the coupling of adjacent touching nerve fibers caused by the exchange of ions between the cells, or it ephapgic refer to coupling of nerve fibers as a result of local electric fields. The local field couplig LFPused to study neural interactions during various brain states, is regarded meurons an epiphenomenon of coordinated neural activity.
Ephaptic coupling – Wikipedia
StaceyChristopher M. It was found that rhythmic electrical discharge associated with fetal neurons in the rat spinal cord and medulla was still sustained. Epileptic seizures occur when there is synchrony of electrical waves in the brain.
Synchronization of neurons is in principle unwanted behavior, as brain would have zero information or be simply a bulb neurojs all neurons would synchronize. Does ephaptic coupling happen when we eat and drink? Editorial on the Special Issue: We hypothesize the functional role of such coupling in various brain states, for example, during visual processing Anastassiou, Encyclopedia for Computational Neuroscience, Springer, Ephaptic coupling strength depends both on the field strength as measured at the neuron soma as well as the spike-history of neurons.
They tested the effects of changing extracellular space which affects local electrical fields and found that one can block epileptic synchronization independent of chemical synapse manipulation simply by increasing the space between cells. Whether it is a true lack of evidence or simply obstinance in the face of change, many in the field are still not entirely convinced there is unambiguous evidence of ephaptic coupling.
These findings support a model in which ephaptic coupling works alongside canonical synapses to propagate signals across neuronal networks. Login Required This action requires you to be registered with Frontiers and logged in. Possible Contribution of Astroglial Magnetic Fields? New Cortical Neuron Types.