KETOASIDOSIS DIABETIKUM PDF

Transcript of Ketoasidosis Diabetikum. Pengantar Tahun , pasien rawat inap KAD rata-rata lama menginap hari. Kelalaian. Download Citation on ResearchGate | Gambaran Klinis Ketoasidosis Diabetikum Anak | Penelitian ini dilakukan untuk menggambarkan profil klinis ketoasidosis. Penelitian ini dilakukan untuk menggambarkan profil klinis ketoasidosis diabetikum pada anak. Data dikumpulkan dari rekam medik gambaran klinis pasien.

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Symptoms of possible associated intercurrent infection may include fever, dysuria, coughing, malaise, and arthralgia, among others.

Ketoasiidosis to an intensive care unit or similar high-dependency area or ward for diabefikum observation may be necessary. Kolesterol dan kadar trigliserida serum dapat meningkat menandakan ketidakadekuatan kontrol glikemik dan peningkatan propensitas pada terjadinya aterosklerosis. If the corrected sodium level remains low, hypertriglyceridemia secondary to uncontrolled diabetes should be also suspected. Dehidrasi disebabkan mekanisme ginjal dimana tubuh terjadi hiperglikemia, sehingga ginjal mensekresikan dengan natrium dan air yang disebut poliuri.

If potassium levels fall below 3. Metabolic acidosis in the alcoholic: A study in adolescents with type 1 diabetes suggests that some of the risk factors for DKA include higher HbA1c, uninsured children and psychological problems Fatty acids, lipotoxicity and insulin secretion. High glucose levels spill over into the urine, taking water and solutes such as sodium and potassium along with it in a process known as osmotic diuresis. Most recently, two new classes of medications have emerged as triggers for DKA.

More frequently, the initial serum potassium diabetikm is normal or low which is a danger sign.

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MAKALAH Keto Asidosis Diabetikum

By continuing to use this website, you agree to their use. The patients received subcutaneous rapid-acting insulin doses of 0. These ketosis-prone type 2 diabetic patients develop sudden-onset impairment in insulin secretion and action, resulting in profound insulinopenia Acetone metabolism in humans during diabetic ketoacidosis.

Ketone body production and disposal: Diabetic ketoacidosis in a community-based population. Positif secara mencolok g.

Age-Adjusted DKA hospitalization rate per 1, persons with diabetes and in-hospital case-fatality rate, United States, — 4. The exact etiology of this non-specific leukocytosis is not known. Ketones, in particular beta hydroxybutyrate, induce nausea and vomiting that consequently aggravate fluid and electrolyte loss already existing in DKA. The released triglycerides and amino acids from the peripheral tissues become substrates for the production of glucose and ketone bodies by the liver Phosphate Therapy There is no evidence that phosphate therapy is necessary in treatment for better outcome of DKA The administration of continuous IV infusion of regular insulin is the preferred route because of its short half-life and easy titration and the delayed onset of action and prolonged half-life of subcutaneous regular insulin.

Drugs in the gliflozin class SGLT2 inhibitorswhich are generally used for type 2 diabetes, have been associated with cases of diabetic ketoacidosis where the blood sugars are not significantly elevated “euglycemic DKA”. N Engl J Med ; Predisposing factors for the diabetic hyperosmolar state.

Hyperglycemic crises in adult patients with diabetes: Respiratory compensation of this acidotic condition results in rapid shallow breathing Kussmaul respirations. J Toxicol Clin Toxicol ; If the patient is unable to eat, it is preferable to continue the intravenous insulin infusion kteoasidosis fluid replacement. Diabetes care ; 3: Frequent blood glucose monitoring at home makes Diabetjkum less likely to occur in such patients because they always can search, in a timely manner, for possible reasons for unexpectedly high blood glucose values before the condition progresses to DKA.

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Diabetic ketoacidosis

Syaraf Neuropati Diabetik Neuropati diabetik adalah akibat kerusakan pada saraf. Occasionally, patients with HHS may present with focal neurological deficit and seizures 72 ketoasldosis, Pada infeksi atau stress berat, baik pada diabetes tipe 1 maupun 2, bisa pula timbul KAD dimana tubuh membentuk hormone adrenalin untuk mengatasi infeksi dan stress, tetapi bisa berdampak negative karena glukosa darah meningkat adrenalin bersifat counterinsulin.

Abstract Penelitian ini dilakukan diabetikun menggambarkan profil klinis ketoasidosis diabetikum pada anak. Akibat diuresis osmotik, KAD biasanya mengalami dehidrasi berat dan bahkan dapat sampai menyebabkan syok.

Gambaran Klinis Ketoasidosis Diabetikum Anak | Aji C | Jurnal Kedokteran Brawijaya

Patofisiologi Konsep Klinis Proses Penyakit. Selain itu nefropati diabetik bisa menimbulkan gagal jantung kongesif.

Anak, gambaran klinis, ketoasidosis diabetikeum. Can serum ketoqsidosis be used to diagnose diabetic ketoacidosis? Hyperglucagonemia in diabetic ketoacidosis. National Institute for Health and Care Excellence.

Therefore, DKA must be excluded if high anion gap metabolic acidosis is present in a diabetic patient treated with SGLT-2 inhibitors irrespective if hyperglycemia is present or not.

Adapted from Kitabchi et al. Hong Kong Medical Journal. A Pooled Analysis of 31 Observational Studies.